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International Journal of Pharmaceutical and Clinical Research ; 14(5):683-692, 2022.
Article in English | EMBASE | ID: covidwho-1913185

ABSTRACT

Recent COVID19 pandemic was evident with increase in cases of mucormycosis which primarily affects the paranasal sinuses, orbits and central nervous system. Depending on organ of involvement, Mucormycosis is further sub-classified of which rhino-orbital-cerebral mucormycosis (ROCM) is most common. In this case series of 5 patients we will see the pattern of neuroaxis involvement along with their radiological features. All patients were suffering with COVID19 confirmed by positive RT PCR results and mucormycosis with KOH mounts. First case was of right frontal abscess with pachymeningeal thickening of right cavernous sinus, right ICA thrombosis and right 5th cranial neuritis. Second case was of right temporal abscess, right ICA & cavernous sinus thrombosis. Third case was of right temporal abscess with pachymeningeal thickening of right cavernous sinus. Fourth case is of right temporal abscess with right middle cranial fossa pachymeningitis and final fifth case was with left ICA thrombosis with skull base osteomyelitis with clivus involvement of mucormycosis. Diagnosis of neuroaxis involvement was done by Computed tomography and Magnetic resonance Imaging. Imaging is very important in diagnosing and studying the pattern of neuroaxis involvement of mucormycosis along with further treatment planning.

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